Gif Central boasts hundreds of funny animated gifs. Only the best of the best make it onto this site, with most of them having an accompanying source. No tumblr-esque one-second-long disappointments. No obscure titles or descriptions.
This is an animated gif of one of those rage face comic characters taking off his sunglasses and saying "Mother of God" before looking on in shock and awe. Typically used whenever people feel overly surprised about something.