Dukie - The Wire

This is an animated reaction gif of Duquan "Dukie" Weems pulling his hoodie up over his head before walking away in disappointment / annoyance. This is from the TV show The Wire. He was portrayed by New York City actor Jermaine Crawford.

Oh, pardon me Mr Perfect!

This is an animated gif of Jim Carrey saying "Oh, well, pardon me Mr Perfect! I guess I forgot that you never ever make a mistake!" This is from the movie Dumb and Dumber (1994), in which Carrey portrayed the character Lloyd Christmas.

Black guy falls off treadmill

This is a funny animated gif of a black guy falling off of a treadmill. The way he dances around before jumping on. The way his shoes go flying off into the air. Hilarious. Sometimes, this gif is used as an analogy for failure.

Rick Moranis - What?!

This is an animated reaction gif of Rick Moranis turning around and saying "What?" This is from the movie Spaceballs (1987), in which Moranis portrays the character Lord Dark Helmet, who is essentially a comedic parody of Darth Vader.

Angry Panda smashes office desk

This is an animated gif of an angry man in a panda suit smashing up somebody's desk in an office before slamming the keyboard off his desk. Not entirely sure where this is from.

Sloth - Shhh, only dreams now

This is an animated gif of a sloth putting its paws / hands over a cats face while the text "Shhh, only dreams now..." appears.

Chloe Moretz

This is an animated reaction gif of Chloe Moretz with a confused / distressed facial expression after she's asked a question during a TV interview. Chloë Grace Moretz is an American actress from Atlanta, Georgia who has starred in movies such as The Amityville Horror (2005) and Let Me In (2010).

You can't handle the truth

This is an animated reaction gif of actor Jack Nicholson shouting "You can't handle the truth!". This was during his role as Col Nathan R. Jessup in the movie A Few Good Men (1992).

Related: You're goddamn right I did!

Ryan - It wasn't me

This is an animated reaction gif of Ryan Howard saying "It wasn't me. It wasn't me. It was not me." The way his facial expression turns from laughter to seriousness makes this gif a great one to use whenever you want to deny doing something. Ryan is a character in the TV show The Office (US).

Jennifer Lawrence - What?!

This is an animated gif of Louisville, Kentucky actress Jennifer Lawrence looking shocked and surprised before shouting "What?!" during an interview. Looks to be during an awards ceremony.

Abandon Thread

This is an animated gif of a bunch of people jumping into a hole while the text "abandon thread" is flashing. Typically used when somebody posts something that others don't want to see or read.

Immune System

This is an interesting animated gif that shows you how your immune system works. Here we see a white blood cell chase after a piece of bacteria until it catches it and engulfs it.

Michael Scott - I'll Kill You

This is an animated reaction gif of Michael Scott quietly saying "I'll kill you" while he conceals his face with his hands. This is typically used whenever somebody wants to tell somebody to knock it off. This is from the TV show The Office (US).

Floating Hedgehog

This is an animated gif of a hedgehog floating on its back in water. Yep. Apparently, they can float.

Adam Workaholics - Sup

This is an animated reaction gif of Adam Dwayne DeMamp squinting his eyes before saying "Sup". A character in the sitcom Workaholics, he is portrayed by Waterloo, Iowa actor Adam DeVine, who is one of the co-creators of the show.

Morgan Freeman Getting Up From Table

This is an animated gif of Morgan Freeman looking unhappy before briskly getting up from the table and walking away. Perfect reaction to use whenever you feel as if the conversation isn't for you or somebody has said something that is too stupid or ridiculous to entertain. This is from the critically acclaimed movie The Shawshank Redemption (1994), in which Freeman portrayed the character Ellis Boyd "Red" Redding.

Kid trying to kick ball

This is a funny animated gif of a kid trying (but failing, badly) to kick a ball. The way the poor boy stumbles and falls over after he miss-kicks is hilarious. This is sometimes used as a reaction gif to convey failure.

Vince McMahon Walk

This is an animated gif of WWE owner Vince McMahon proudly walking / power-walking down past the Titantron during a wrestling event. McMahon has a net worth of 1.1 Billion dollars. I seen this one with the title "walking out of the bathroom after a nice poop".

I'm not sure what to do with my hands

This is an animated gif Will Ferrell saying "I'm not sure what to do with my hands". This is from the movie Talladega Nights: The Ballad of Ricky Bobby, in which Ferrell portrayed the character Ricky Bobby.

Horse Crapping on Woman's Head

This is a funny animated gif of a horse pooing / crapping on top of a woman's head after she decided to stick her head between its legs and shout "peekaboo".

Buck Showalter High Five

This is an animated gif of Major League Baseball manager Buck Showalter being left hanging as he tries to give one of his players (Reynolds) a high five. The defeated thumbs up that he gives at the end is just hilarious.

Steven Gerrard Fail

This is a funny animated gif of Liverpool midfielder Steven Gerrard completely missing the football before falling to the ground in pain. Stevie G has been playing for Liverpool since his debut in 1998.

Black Kid Crying

This is an animated gif of a black kid crying as a single tear rolls down his face. Not sure where this is from.

Zeb Colter

This is animated reaction gif of manager Zeb Colter looking extremely angry. Colter is a character in WWE. He is portrayed by Wayne Maurice Keown.

Shuckle

This is an animated gif of a bunch of Shuckle with hearts for eyes waving their arms around in the air and licking their lips. This is often used as a reaction to convey a mass group of people swooning over something. The creepiness adds that extra effect. A Shuckle is a type of Rock / Bug Pokémon.

Robin Williams Smile

This is an animated reaction gif of actor Robin Williams smiling. Williams is from Chicago, Illinois. He's famous for starring in movies such as Mrs. Doubtfire, Jumanji and Patch Adams.

Mussolini

This is an animated gif of Italian dictator Benito Mussolini folding his arms and nodding his head. This is sometimes used as a reaction whenever somebody is trying to convey their approval of something. Mussolini was the leader of the National Fascist Party in Italy. He was called "Il Duce", which translates into "The Leader".

Emilia Clarke

This is an animated gif of English actress Emilia Clarke expressively moving her eyebrows during a TV interview. Emilia is mostly famous for her portrayal of Daenerys Targaryen (khaleesi) in the popular HBO show Game of Thrones.

We Have To Go Back

This is an animated reaction gif of Jack Shephard from Lost saying "We Have To Go Back" (to the island). The character is portrayed by Abington, Pennsylvania actor Matthew Fox.

IED Explosion

This is an animated gif of what looks to be an IED Explosion. Imagine that. You're just driving along and then boom, a massive fireball is engulfing the sky. In case you didn't already know, IED stands for improvised explosive device. Basically, it is a type of homemade bomb that is extremely popular among guerrilla forces in Iraq and Afghanistan.

Jennifer Lawrence - Yoga Pants

This is an animated gif of Jennifer Lawrence dancing in some white yoga pants during her role as Tiffany Maxwell in the movie Silver Linings Playbook (2012). It was this role that won Lawrence her Best Actress award during the 2013 Oscar Awards.

Cat chasing light

This is a funny animated gif of a cat going absolutely crazy / ballistic as it chases and tries to catch a beam of light that is being shone onto the floor.

Dennis Rodman and Karl Malone falling over

This is probably the funniest gif that I've seen in a while. Here we have basketball stars Dennis Rodman and Karl Malone repeatedly tripping and falling over one another. I'm actually amazed at how long this goes on for. Rodman was playing for the Chicago Bulls and Malone was playing for the Utah Jazz. Both men are now retired.

Surfing river rapids

This is a cool animated gif of a guy surfing the rapids of a river. In case you didn't already known, a rapid is basically a section of a river where the water is flowing at a faster velocity (due to a steep gradient). From what I've read, this isn't particularly dangerous as he is surfing what looks to be a class-2 wave train. This means that he can easily swim ashore if he tips over.

Deer being scratched

This is an adorable animated gif of a deer being scratched by somebody. What makes this gif so great is how pleased the deer is with being petted.

The D is Silent

This is an animated gif of Jamie Foxx in Django Unchained mouthing the words "The D is silent". Foxx portrayed the character Django Freeman.

Fez - I love you

This is an animated reaction gif of Fez from That 70's Show making a heart shape with his hands while mouthing the words "I love you". He is portrayed by Miami, Florida actor Wilmer Valderrama.

Cat in bee suit

This is a funny animated gif of a cat wearing a bee suit. The person with the camera frightens the cat and it ends up falling off the couch.

Owl

This is an animated gif of a nosy owl peeking / peering its head around the corner while somebody holds a hand up in front of its face.

Van Damme punching snake

This is an animated gif of Van Damme punching a snake and knocking it out. Hilarious in its absurdity. Not sure what movie this is from but I'm guessing that it is badass.

Zoidberg Dumpster

This is an animated reaction gif of Futurama character Zoidberg looking rather down and out before he finally decides to crawl into a dumpster. This is typically used as a reaction whenever somebody feels overwhelmingly sad about something.

Mailbox Kid

This is a hilarious animated gif of an unsuspecting kid getting mail shoved into his mouth while he's looking through the mailbox of his front door. To make things even worse, the poor boy falls off his toy truck and onto the ground.

Clint Dempsey Facial Expression

This is an animated reaction gif of American soccer player Clint Dempsey pulling a funny facial expression. Dempsey currently plays for Tottenham Hotspur F.C.

Baseball Catch

This is an animated gif of a baseball player Evan Longoria turning around and catching a baseball while it flies in the direction of him and a female reporter. I'm pretty sure that I remember reading that this was fake / setup. Funny nonetheless.

Praying Mantis LOL

This is an animated gif of a Praying Mantis typing LOL on a keyboard.

Raising Eyebrows

This is an animated reaction gif of a man repeatedly raising / lifting his eyebrows in a suggestive / perverted manner. Not sure where this is from, so if you know, please post a comment in the section below.

Bee Crash

This is a rather interesting slow motion gif of a mid-air collision between two flying bees. The way they both fall to the ground is pretty cool.

Ksenia Solo - Tick Tick Boom

This is an animated gif of Ksenia Solo saying "Tick Tick Boom! Time Bomb!" This is from the Canadian television series Lost Girl, in which Ksenia portrays the character Kenzi. Ms Solo is a Latvian-born Canadian actress who also played the character Tasha on Life Unexpected.

Robert Downey, Jr. taking off his glasses

This is an animated gif of Robert Downey, Jr. dramatically taking off his glasses while entering an awards show or a premier. Not sure where this was taken. Maybe it was at the Iron Man 3 premier (just a guess)?

Skateboarder Falling

This is a funny animated gif of a skateboarder falling down some steps. The thing that makes this skateboard fail so hilarious is how prolonged the fall is. It takes about six seconds before he has finally stopped flailing around.